MacOS Sierra broke support for the only driver, Wjoy, but it was updated on a new fork.
System-wide use is technically supported, but we heavily recommend finding a new controller. Mac is supported in the same way-only in Dolphin. Dolphin, the Wii emulator, supports using them as inputs, but we didn’t have any on hand to test system-wide use. Windows will connect the controller by default, but it may not be usable as a controller in all apps. RELATED: How to Connect the Nintendo Switch Joy-Con or Pro Controllers to Your PC Wii Remotes and Wii U Pro Controllers Nintendo’s Switch Pro controller works automatically after you connect it via Bluetooth on Windows and macOS, but you’ll have to set it up in Steam to use in games. Also, if you’re crazy, you can forego the adapter altogether and splice together a couple of cables, although we don’t recommend this. MacOS has an older driver, but it may not work on newer versions of macOS. You’ll need an adapter and some custom drivers, but it doesn’t seem entirely easy. Due to problems with kernel extensions (kexts,) wireless support causes kernel panics, and is disabled in this driver.